Hypoxic secretome mesenchymal stem cells inhibiting interleukin-6 expression prevent oxidative stress in type 1 diabetes mellitus
Aim Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by the chronic inflammation of the pancreatic islets of Langerhans. Hyperglycaemia leads to suppressed antioxidant enzyme and increased inflammation in the pancreatic cell, resulting in pancreatic cell death. Hypoxic secretome mesenchymal stem cells (HS-MSCs) are soluble mol...
By Ayuningtyas Utami, Agung Putra, Joko Wahyu Wibowo, Amalina Nur Dina, Risky Chandra Satria Irawan
Red algae extract suppresses caspase-3 gene expression and induces catalase antioxidant enzyme in testicles of rats induced by boric acid
Aim To determine the effect of red algae extract on the gene expression of catalase and caspase-3 in testicules of rats induced by boric acid (BA).Methods This is experimental research with post-test control group design. Twenty four healthy male Wistar rats were divided intofour treatment groups: a healthy group, negative control group, two treatm...
By Ayu Renda Sari, Joko Wahyu Wibowo, Sri Priyantini, Agung Putra, Nur Dina Amalina