Mesenchymal stem cells under hypoxia condition inhibit peritoneal adhesion by suppressing the prolonged release of interleukin-6
Aim To investigate the role of hypoxia-preconditioned mesenchymal stem cells (H-MSCs) in preventing peritoneal adhesionby regulating IL-6 at days 6 and 12.Methods Twenty-four PAs rat model weighing 250 g to 300 g were randomly allocated into 4 groups: sham (Sh), control (C),H-MSCs treatment group at dose 1.5 x 106 (T1) and 3 x 106 (T2). To in...
By Adi Muradi Muhar, Agung Putra, Vito Mahendra Ekasaputra, Dewi Masyithah Darlan, Desiree Anggia Paramita, Iqbal Pahlevi Adeputra Nasution
Interleukin-8 heterozygous polymorphism (-251 T/A and +781 C/T) increases the risk of Helicobacter pylori-infection gastritis in children: a case control study
Aim To investigate the effects of interleukin-8 (IL-8)-251 T/A and +781 C/T polymorphism on the risk of Helicobacter pyloriinfection gastritis in children, and the IL-8 level of children with or without gastritis H. pylori infection according to polymorphism. Methods This prospective, case control clinical study included 64 children 2-18 years old....
By Dr Supriatmo, Gontar Alamsyah Siregar, Iqbal Pahlevi Adeputra Nasution, Oke Rina Ramayani